Virgin Coconut Oil for HIV - Positive People
Abstract
The objective of the study was to determine effects of 3 x 15 ml/day Virgin Coconut Oil supplementation for 6 weeks in subject to CD4+ T lymphocyte concentration and conducted at Special health center on Dharmais Cancer Hospital, Jakarta. The methods involved experimental study with parallel design on 40 HIV subject with CD4+ T lymphocyte count > 200 cell/µL divided into two groups, VCO group, subject in this group received VCO supplementation 3 x 15 ml/day for 6 weeks and non-VCO Group (without VCO supplementation). Data collected includes demographic characteristic (age and sex), anthropometric (weight, height, and body mass index), daily intakes by food recall 1 x 24 hours and laboratory (CD4+ T lymphocyte count). Statistical analysis was performed with independent t test and Mann-Whitney U test. The results could be summarised as follows. The average BMI were 20.8 ± 2.29 kgs/sqm (VCO group) and 20.7 ± 3.38 kgs/sqm (non-VCO group). Energy and fat intake between VCO group (1459 ± 327.4 Cal/day and 81.8 ± 19.35 gs/day) and non-VCO group (1101 ± 319.8 Cal/day and 37.1 ± 19.35 gs/day). Carbohydrate and protein intake between VCO group (143.8 ± 44.58 gs/day and 41.6 ± 14.04 gs/day) and non-VCO group (151.6 ± 14.04 gs/day and 39.5 ± 18.31gs/day). There were significant differences (p = 0.047) in average of CD4+ T lymphocyte count after 6 weeks intervention between VCO group (481 ± 210.0 cell/µL) and non-VCO group (343 ± 129.1 cell/µL). The conclusion is that Virgin Coconut Oil supplementation 3 x 15 ml/day for 6 weeks increases CD4+ T lymphocyte concentration in HIV patient.
References
Dayrit C.S. (2000) Coconut oil in health and disease: its and monolaurin’s potential as cure for HIV/AIDS. XXXVII Cocotech Meeting. Chennai, India. http://www.coconutresearchcenter.com. Access on 28th December 2006.
Enig M.G. (1998) Lauric oils as antimicrobial agents: theory of effect, scientific rationale, and dietary application as adjunct nutritional support for HIV-infected individuals, in Nutrients and Foods in AIDS (editor Watson R.R.). Page 81 – 97. CRC Press, Florida.
Hatma R.D. (2001) Nutrient intake and their relation to lipid profile in diverse ethnic population, Dissertation. Post Graduate Program, University of Indonesia, Jakarta.
Kamps B.S. and Hoffmann C. (2005) Introduction, in HIV Medicine 2005 (editor Hoffmann C., Rockstroh J.K., and Kamps B.S.). Page 23 – 32. Flying Publisher, Paris.
Klein S., Cohn S.M., and Alpers D.H. (1999) The alimentary tract in nutrition: a tutorial, in Modern Nutrition in Health and Disease (editor Shils M.E., Olson J.A., Shike M., and Ross C.A.). 9th Ed, page 605 – 629. William & Wilkin, Pennsylvania.
Kotler D.P. (1992) Nutritional effects and support in the patient with acquired immunodeficiency syndrome. J. Nutr. 122 (Suppl. 3), 723 - 727.
Macallan D.C., Noble C., Baldwin C., Jebb S.A., Prentice A.M., and Coward W.A. (1995) Energy expenditure and wasting in human immunodeficiency virus infection. N.Engl.J.Med. 333(2): 83 – 88.
Muhilal, Jalal. F., and Hardinsyah (1998) Angka kecukupan gizi yang dianjurkan. dalam Prosiding Widyakarya Nasional Pangan dan Gizi VI Serpong 17-20 Februari 1998. (editor Winarno F.G., Tsauri S., Soekirman, Sastrapradja D.S., Wirakartakusumah M.A., Rifai M.A., Jalal F., Suryana A., Husaini M.A., Atmowidjojo M., and Koswara S.) page 843-879. Lembaga Ilmu Pengetahuan Indonesia. Jakarta.
Nugraha G.I. (2005) Profil lipid dan apolipoprotein A-I serta faktor-faktor yang berhubungan pada perajin minyak kelapa di Jawa Barat. Thesis.
Odle J. (1997) New insights into the utilization of medium-chain triglycerides by the neonate: observations from a piglet model. J. Nutr. 127, 1061 – 1067.
UNAIDS (2004) Report on the global AIDS epidemic: executive summary. http://www.unaids.org. Access on 2nd January 2006.
Scrimshaw N. and SanGiovanni J.P. (1997) Synergism of nutrition, infection, and immunity: an overview. AJCN 66(2), 464-477.
Sujudi A. (2002) Penanggulangan HIV/AIDS di Indonesia respon saat ini-menangkal ancaman bencana nasional AIDS mendatang. Disampaikan dalam Sidang Kabinet Sesi Khusus HIV/AIDS. Jakarta.
Walker D. (2003) Cost and cost-effectiveness of HIV/AIDS prevention strategies in developing countries: is there an evidence base? Health Policy Planning 18(1), 4 – 17.
Takatsuki A., Tamura G., and Arima K. (1969) Antiviral and antitumor antibiotics. Effects of ascochlorin and other respiration inhibitors on multiplication of newcastle disease virus in cultured cells. Applied Microbiology 17(6), 825 – 829.
Thormar H., Isaacs C.E., Brown H.R., Baarshatzky M.R., and Pessolano T. (1987) Inactivation of enveloped viruses and killing of cells by fatty acids and monoglycerides. Antimicrob. Agents Chemother. 33(1), 27 – 31.
